Senior Pharmacometrician
The arena 
AstraZeneca is one of the leading pharmaceutical companies, active in over 100 
countries. We have 13,000 people dedicated to R&D, with centres of research 
excellence in the UK, US, Sweden, Canada and India. Over £7million is invested 
each working day to ensure a flow of new medicines that makes a difference. AZ 
is focusing on four therapy areas: Cardiovascular & Gastrointestinal, Oncology 
& Infection, Respiratory & Inflammation, and Neuroscience. 
Clinical Pharmacology & DMPK (Clin Pharm&DMPK) is a newly formed global 
department within the Clinical function in R&D. It covers expertise in 
modelling and simulation (pharmacometrics), clinical pharmacology (including 
CPUs), pharmacokinetics, drug metabolism and bioanalysis. Clin Pharm&DMPK is 
involved in project work from CD selection through life cycle management of AZ 
compounds. Clin Pharm&DMPK is now expanding its model based drug development 
initiative and is looking for a senior pharmacometrician to join the global 
network lead by a Global Pharmacometrics Discipline Lead. Clin Pharm&DMPK is 
located on six R&D sites, Mölndal, Södertälje and Lund in Sweden, Manchester 
and Charnwood in the UK, and Wilmington in the US. The position could be placed 
on any of the sites. 
The role 
In your role as a senior pharmacometrician you will be responsible for 
population PK and PK/PD modelling, exposure response and disease modelling, as 
well as other modelling & simulation components throughout the drug development 
process. 
You will work closely together with Clin Pharm&DMPK Leaders, 
pharmacokineticists, medics, and biostatisticians and you will be a member of 
the global AZ Pharmacometrics group. 
The preparation of scientific presentations and/or publications will be 
encouraged and there will be opportunities for personal and knowledge base 
development through attendance at in-house or external courses/meetings. 
Minimum experience/requirements 
*       A PhD (Pharmacology, Statistics, Engineering) or post graduate 
qualification, ideally in PK-PD modeling or at least 3-5 years experience in 
drug development 
*       Solid, hands-on experience with population approaches in PK and/or 
PKPD, as well as the use of modelling and simulation techniques to support 
decision making
More information 
For more information please contact Tommy Andersson, AstraZeneca R&D Mölndal 
Sweden, tel. +46 (0) 31 776 10 09 or +46 (0) 708 46 74 29 or Bengt Hamrén, +46 
(0) 31-776 11 08. 
Closing date is 11 June 2008 
Job-Clinical Development 
Primary Location-Sweden 
Other Locations-UK, USA 
Schedule-Full-time 
Job Posting:29-May-08 -- 11-Jun-08
For more information and to apply for the position see: www.astrazeneca.com 
(Careers)

________________________________
Bengt Hamrén, PhD
Senior Research Scientist
Clinical Pharmacology and DMPK
AstraZeneca R&D Mölndal
S-431 83 Mölndal, Sweden
Phone: + 46 31 776 11 08
Email: [EMAIL PROTECTED]

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