Hi all, We've run into some problems with NONMEM V and occasionally VI hanging during minimization (the "black hole" phenomenon, in which NONMEM stops iterating, but never terminates, indefinitely continuing to occupy 99% of the CPU it's running on), using GNU g77 3.4.6 on Red Hat Linux - I guess this is most likely related to g77's virtually non-existent handling of floating point errors.
One way to address this would be to compile the trapfpe.c routine that's floating around the Internet into the NONMEM library, I think, but I can't help wondering whether there is a more elegant fix (apart from writing less buggy NONMEM code). Has anyone had any recent experience with dealing with this? If we were to dump g77 altogether, what other compilers are known to work adequately with NONMEM on Linux? Best regards, Justin Justin Wilkins Novartis Pharma AG PH346, MODELING & SIMULATION CHBS, WSJ-027.1.084 Novartis Pharma AG Lichtstrasse 35 CH-4056 Basel Switzerland Phone: +41 61 324 6549 Fax: +41 61 324 3039 Mobile: +41 76 561 0949 Email : [EMAIL PROTECTED]
