Ayyappa,

As far as I know any 'classical statistical analysis' that one can do using regression can be done with NONMEM. It is also possible to do hypothesis testing on means (t-test, ANOVA), logistic regression and survival analysis. What kinds of 'classical statistical analysis' do you want to do that you cannot do with NONMEM?

Nick


[EMAIL PROTECTED] wrote:

Dear Group,

Could anybody explain or direct me to some literature why population PK approach allows us to pool data from different studies but no classical statistical analysis?
Regards,
Ayyappa Chaturvedula
GlaxoSmithKline
1500 Littleton Road,
Parsippany, NJ 07054
Ph:9738892200

--
Nick Holford, Dept Pharmacology & Clinical Pharmacology
University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand
[EMAIL PROTECTED] tel:+64(9)923-6730 fax:+64(9)373-7090
http://www.fmhs.auckland.ac.nz/sms/pharmacology/holford

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