Dear NMUSERS,

A few years back, there was a discussion on the P-value for ETABAR. However, I 
am not sure how to appropriately handle very small P-value(s) for ETABAR 
situation during the development of a model. 

I need some clarifications to a few questions:
1: Should we just ignore this small P-Value warning? 
2: Can we change IIV model to avoid small P-value for ETABAR? Or any other 
suggestions? 
3: Does NONMEM make any assumptions on ETA distribution?

This P-value for ETABAR really bugs me a lot. I look forward to seeing some 
input.

Thank you and I appreicate your time and help.

Jian


      

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