Dear NMUSERS, A few years back, there was a discussion on the P-value for ETABAR. However, I am not sure how to appropriately handle very small P-value(s) for ETABAR situation during the development of a model.
I need some clarifications to a few questions: 1: Should we just ignore this small P-Value warning? 2: Can we change IIV model to avoid small P-value for ETABAR? Or any other suggestions? 3: Does NONMEM make any assumptions on ETA distribution? This P-value for ETABAR really bugs me a lot. I look forward to seeing some input. Thank you and I appreicate your time and help. Jian