Hi Nick, Coen, all, I would go one step further and suggest IGNORE=@ instead of IGNORE=# (the same as leaving out the IGNORE option). This has the advantage of ignoring all lines starting with alphabetic characters in the data file, such as those belonging to column headings, as well as I, C, and any other alphabetical character you want to use for commenting - while allowing the use of the column header row for other purposes such as manipulation of the data in other software such as R without the need for any complicated importing rules. You could even use this to include a column containing the reason for dropping a row, e.g.
IGNORE ID TIME DV ... . 1 0 0 . 1 0.25 0.316 Sample thawed 1 0.5 0.0776 . 1 1 0.419 ... although it must be said that this data structure seems to create issues with PsN. Best Justin Justin Wilkins Senior Modeler Modeling & Simulation (Pharmacology) CHBS, WSJ-027.6.076 Novartis Pharma AG Lichtstrasse 35 CH-4056 Basel Switzerland Phone: +41 61 324 6549 Fax: +41 61 324 1246 Cell: +41 76 561 0949 Email : justin.wilk...@novartis.com Nick Holford <n.holf...@auckland.ac.nz> Sent by: owner-nmus...@globomaxnm.com 23/04/2009 09:33 To nmusers <nmusers@globomaxnm.com> cc Subject [NMusers] Re: PharmPK Re: NMTRAN error Coen suggests using # as the ignore character and proposes to add IGNORE=# to the $DATA record. In fact things can be simpler than that. The default value for IGNORE is # so if you use # in your data file you dont have to waste time adding IGNORE=# :-) I dont know where this strange idea of ignoring the default and using C comes from -- but it is an unfortunate way to teach people how to use NM-TRAN. Coen van Hasselt wrote: > PharmPK - Discussions about Pharmacokinetics > Pharmacodynamics and related topics > > > The following message was posted to: PharmPK > > Hi, > > It seems you have forgotten to tell NONMEM not to treat the header > line in your datafile as an actual data record, i.e. to ignore it. > > Lets say your datafile header line looks like: ID TIME DV ... etc., > then you can tell NONMEM to ignore lines starting with the character > "I" by: $DATA datafile.csv IGNORE=I. > > A lot of people prefer putting a # as the first character of the > header line of your datafile, so: #ID TIME DV .. etc. > Obviously, for your $DATA you then use IGNORE=#. > > Good luck. > > Coen > > -- > An archive index, search page and subscription form can be found at > http://www.boomer.org/pkin/ > Note: All messages (except job listing and conferences) are archived > (eventually) online and are searchable > PK/PD Jobs can be found at > http://www.boomer.org/pkin/pkjob.html > > > -- Nick Holford, Dept Pharmacology & Clinical Pharmacology University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand n.holf...@auckland.ac.nz tel:+64(9)923-6730 fax:+64(9)373-7090 mobile: +33 64 271-6369 (Apr 6-Jul 17 2009) http://www.fmhs.auckland.ac.nz/sms/pharmacology/holford
