Modeling and Simulation Visiting Scientist Position at Novartis 
Pharmaceuticals 


The company: a global healthcare leader, Novartis has one of the most 
exciting product pipelines in the industry today. A pipeline of innovative 
products brought to life by diverse, talented, performance-driven people. 
All of which makes us one of the most rewarding employers in our field.

Modeling and Simulation at Novartis: supports the optimal development of 
therapeutic drugs. Modeling & Simulation (M&S) integrates the principles 
of biology, pharmacology, and statistics to explain and predict the 
quantitative consequences of decisions, through the application of 
mathematical models. A dedicated programming group facilitates our 
activities by providing data extraction and integration. M&S is a Global 
Line Function which reports directly to the Global Head of Development. 
M&S is committed to provide excellence in quantitative support for 
informed decision-making throughout the organization, from Research 
through to Development, regulatory approval and the market place.

The task: We are looking for innovative and motivated quantitative 
scientist with a genuine interest in disease modeling and meta analyses 
and has a solid scientific background in mixed effect modeling and 
simulation, including basic programming skills. S/he should have a general 
understanding of immune disorders and is willing to gain a deeper insight 
in rheumatoid arthritis (RA) in particular.
The aim of this project is to establish a model framework that captures 
all important components of the longitudinal changes of key clinical 
measures in RA, including the effects of disease and different therapeutic 
regiments on the disease progression processes. 
Activities for the visiting scientist will include, but are not limited 
to, supporting quantitative aspects of model development, interacting with 
clinicians to align model building strategies, communicate modeling 
results and support publications.


Ideal candidate:
Modeling skills: 
Understanding and experience in modeling of longitudinal clinical data
Some experience in modeling of summary level data e.g. using Bayesian 
methodologies
Model building and validation, including non linear mixed effect modeling
 Biological/Pharmacological domain 
Knowledge and experience in pharmacokinetic-pharmacodynamic modeling
Basic knowledge of immune disorders
Knowledge on how to extract and use information/data from literature


To apply, go to www.novartis.com (Careers) and the position has the 
following Job ID: 57470BR 

For more information please contact Bengt Hamrén (contact info below) or 
Colin Pillai ([email protected], +41 61 324 6025) 


Bengt Hamrén, PhD
Novartis Pharma AG
PH332, M&S Pharmacology
CHBS, CHBS, WSJ-027.1.014
Novartis Pharma AG
Forum 1
Novartis Campus
CH-4056 Basel
Switzerland
Phone: +41 61 3245923
Fax: +41 61 3241246
Email : [email protected]


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