Pavel, The message you describe is usually the result of not having enough memory available for the NONMEM 7 memory image. If you are using the "big" version of SIZES you may need about 1.6-2 GB of available memory for each job. For the efficient use of NONMEM 7's new methods more variables are now stored in memory than was the case for NONMEM VI. The memory image is larger even if one is not using the new methods. When using NONMEM 7 and the "reg" SIZES, I have been able to run 8 jobs simultaneously on a dual processor dual core machine, but only 3-4 jobs when using the "big" version of SIZES depending upon what else is running. I have 3 GB of memory and the task manager indicates a maximum of about 7.4 GB via paging. Tom
Thomas M. Ludden Ph.D. Vice-President, Pharmacometrics R&D ICON Development Solutions Tel: + 1 410 696 3040 Mob: + 1 410 258 2411 Fax: + 1 410 480 0776 Email: [email protected] Web: www.icondevsolutions.com <http://emailsignature/stationary/Icon_Development_Solutions.gif> ________________________________ From: [email protected] [mailto:[email protected]] On Behalf Of [email protected] Sent: Friday, October 16, 2009 2:02 PM To: [email protected] Cc: [email protected] Subject: [NMusers] The system cannot execute the specified program > Hello NONMEM Users, > We have a computer with 4 processors. When I try to run more > than 3 NONMEM7 jobs, I am getting the following message: > Starting nonmem execution ... > The system cannot execute the specified program. > KP9022.OUT > newline > 1 file(s) copied. > Could Not Find H:\4\output > > The message is code and directory independent. It always > appears when I try to run more than 3 codes. When I test > nonmem7 using a laptop, which also has 4 processors, I can > execute 4 programs. Also, when I had NONMEM6, I did not have > this problem on the same machine. > Do you familiar with this problem? Thanks. > Pavel > ICON plc made the following annotations. ------------------------------------------------------------------------------ This e-mail transmission may contain confidential or legally privileged information that is intended only for the individual or entity named in the e-mail address. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution, or reliance upon the contents of this e-mail is strictly prohibited. If you have received this e-mail transmission in error, please reply to the sender, so that ICON plc can arrange for proper delivery, and then please delete the message. Thank You, ICON plc South County Business Park Leopardstown Dublin 18 Ireland Registered number: 145835
