I would recommend the following: 1. Set PRINT=9999
This way, iteration 0 is printed, as well as the final results. Unlikely you will have more than 9999 iterations to have any intervening iterations printed. 2. Do not specify the FILE= in a multi-problem statement such as the $SIML NSUB=3 type. The .ext file name will be defaulted to the root name of your control stream file, so you do not have control of its name, but it should not be over-written from one problem to the next, or in a multi-problem statement. Robert J. Bauer, Ph.D. Vice President, Pharmacometrics ICON Development Solutions Tel: (215) 616-6428 Mob: (925) 286-0769 Email: [email protected] Web: www.icondevsolutions.com -----Original Message----- From: [email protected] [mailto:[email protected]] On Behalf Of Sebastien Bihorel Sent: Wednesday, March 10, 2010 4:28 PM To: [email protected] Subject: [NMusers] Questions about the raw output file in NM7 Dear NMusers, I would like to have your help on two issues regarding the raw output file in NM7: 1- when using $ESTIMATION PRINT=0 with "old" estimation methods (FO, FOCE, FOCEI, HYBRID and Laplacian), the raw output files only contain the -1000000000 line plus possibly the -1000000001, -1000000002 and -1000000003 lines. With new estimation methods, the files also contain data at iteration 0. Is there an option we can use with old estimation method to request the iteration 0 data to be written into the raw output files? 2- when an estimation step is requested after a simulation step with NSUB>1, the raw output file only reports the result of the last simulation/estimation run. E.g. when I tried the following code, $SIM (1212345) NSUB=3 $ESTIMATION METHOD=COND FILE=whatever.est PRINT=1 MAXEVAL=5000 NOABORT only TABLE NO. 3 was reported in whatever.est. By stopping the run at different times, I found out that the content of the file is actually overwritten at each sub-problem. Is there a option that would append the new content to the file rather than overwriting it? Thank you in advance for your feedback. Sebastien Bihorel ICON plc made the following annotations. ------------------------------------------------------------------------------ This e-mail transmission may contain confidential or legally privileged information that is intended only for the individual or entity named in the e-mail address. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution, or reliance upon the contents of this e-mail is strictly prohibited. If you have received this e-mail transmission in error, please reply to the sender, so that ICON plc can arrange for proper delivery, and then please delete the message. Thank You, ICON plc South County Business Park Leopardstown Dublin 18 Ireland Registered number: 145835
