BiogenIdec has an open position for a Sr. Scientist/Principal Scientist Modeling and Simulation. The position is located in Cambridge, MA.
Job Description: We are seeking a highly motivated and experienced individual as Sr. Scientist/Assoc Director within the Clinical Pharmacology and Pharmacometrics function of BiogenIdec. This individual must demonstrate strong skills in the discipline of Quantitative Clinical Pharmacology (Pharmacometrics). The individual will develop pharmacostatistical models including disease models, exposure - response models, biomarker - efficacy models, population PK models, etc., throughout all phases of drug development. Knowledge and expertise in various PK/PD modeling techniques, such as nonlinear mixed effect modeling, Bayesian methods, etc., are essential. The Candidate will work as a partner in multi-disciplinary development teams by providing Quantitative Clinical Pharmacology expertise. Effective collaborations with physicians, DMPK scientists, statisticians, clinical pharmacologists and regulatory affairs experts are of key importance. Extensive scientific track record of publications is desirable, and excellent communication and interaction skills in team environment are essential. The successful candidate will have good leadership and collaboration abilities with experience in communicating modeling and simulation results to non-quantitative scientists. Other essential qualities include astute decision making abilities, the ability to drive innovation, build effective professional relationships, and meet goals and deadlines. Qualifications: For the Principal Scientist level, a doctorate degree with demonstrated expertise in pharmacometrics and strong quantitative skills (e.g. experience in statistical and/or mechanistic modeling) is required with approx. 10 years of relevant working experience in industry and/or academia. A Master's degree and other relevant academic training in biostatistics, pharmacometrics and quantitative sciences with commensurate experience are also acceptable. The ideal candidate will have a strong track record that demonstrates in-depth knowledge and experience in the current PKPD modeling software products. The candidate should possess sound understanding of the role and applications of Pharmacometrics in drug development. Familiarity with Good Clinical Practice and applicable FDA/EMA guidelines is highly desirable. Education: Ph.D. MSc, or equivalent in Statistics, Biomedical Engineering, Pharmacokinetics, Pharmaceutical Sciences, or related discipline. Please contact Matt Soloperto (Recruiter-Biogen Idec) matt.solope...@biogenidec.com<mailto:matt.solope...@biogenidec.com> or Ivan Nestorov (Director-Pharmacometrics) ivan.nesto...@biogenidec.com<mailto:ivan.nesto...@biogenidec.com> Ivan Nestorov, PhD Pharmacometrics Bldg. 7, 10 Cambridge Center Cambridge, MA 02142 Office: 617-679-2541 Cell: 857-294-3543 Fax: 617-679-3463 Email: ivan.nesto...@biogenidec.com
