Read the NONMEM output file (the first thing you should always do) and look for clues. See if says anything like "problem with table step", etc.
From: [email protected] [mailto:[email protected]] On Behalf Of Ayyappa Chaturvedula Sent: Wednesday, September 07, 2011 1:52 PM To: [email protected] Subject: [NMusers] Table files are not created Dear All, I have a problem with my TABLE option. I have the following code: $ESTIMATION NOABORT POSTHOC METHOD=ZERO INTER MAXEVAL=9999 PRINT=5 MSFO=run1.msf $COVARIANCE $EST METHOD=ITS INTERACTION FILE=example1.ext NITER=500 PRINT=5 NOABORT SIGL=4 CTYPE=3 CITER=10 CALPHA=0.05 NOPRIOR=1 NSIG=2 $EST METHOD=IMP MAPITER=0 INTERACTION EONLY=1 NITER=5 ISAMPLE=3000 PRINT=1 SIGL=8 NOPRIOR=1 $EST METHOD=BAYES INTERACTION FILE=example1.txt NBURN=10000 NITER=10000 PRINT=100 NOPRIOR=0 $EST METHOD=COND INTERACTION MAXEVAL=9999 NSIG=3 SIGL=10 PRINT=5 NOABORT NOPRIOR=1 FILE=example1.ext $COV MATRIX=R PRINT=E UNCONDITIONAL SIGL=12 $TABLE ID TIME PRED RES WRES CPRED CWRES EPRED ERES EWRES NOAPPEND ONEHEADER FILE=example1.TAB NOPRINT $TABLE ID CL V FIRSTONLY NOAPPEND NOPRINT FILE=example1.PAR $TABLE ID ETA1 ETA2 FIRSTONLY NOAPPEND NOPRINT FILE=example1.ETA $TABLE ID TIME DV IPRED IWRES NOPRINT ONEHEADER FILE=SDTAB1 $TABLE ID AGE GEN HT WT NOPRINT NOAPPEND ONEHEADER FILE=CATAB1 $TABLE ID GEN NOPRINT NOAPPEND ONEHEADER FILE=COTAB1 $TABLE ID CL V ETA1 ETA2 NOPRINT NOAPPEND ONEHEADER FILE=PATAB1 $TABLE ID TIME DV IPRED AMT MDV CL V ETA1 ETA2 CWRES NOPRINT ONEHEADER FILE=RUN1.fit For some reason, my files related XPOSE (CATAB, PATAB etc..) are not created but others are coming fine. The run was successful with all the estimations but having trouble with Table files. I appreciate your help to resolve this. I am using g95 fortran compiler, Windows 7,NONMEM7.2. Ayyappa Chaturvedula, PhD Visiting Assistant Research Professor, College of Pharmacy and Health Sciences, Mercer University, 3001 Mercer University Drive, Atlanta, GA 30341 6785476168 (O) ICON plc made the following annotations. ------------------------------------------------------------------------------ This e-mail transmission may contain confidential or legally privileged information that is intended only for the individual or entity named in the e-mail address. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution, or reliance upon the contents of this e-mail is strictly prohibited. If you have received this e-mail transmission in error, please reply to the sender, so that ICON plc can arrange for proper delivery, and then please delete the message. Thank You, ICON plc South County Business Park Leopardstown Dublin 18 Ireland Registered number: 145835
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