Clinical Pharmacology = Disease Progression + Drug Action by
Nick Holford, MBChB University of Auckland, New Zealand September 19, 2011 3:30 - 4:30 pm EDT This is a reminder that Dr. Holford's webinar Clinical Pharmacology = Disease Progression + Drug Action will take place on September 19, 2011 at 3:30 pm EDT (GMT -5:00). Dr. Holford’s talk will focus on modeling in clinical pharmacology. Like many disciplines, clinical pharmacology can be viewed from several perspectives. In the context of a clinical trial of a therapeutic agent, clinical pharmacology provides a conceptual framework for relating drug treatment to responses and differentiating possible mechanisms of action. Disease progression refers to the evolution of a disease over time. It typically implies worsening of the disease (but also may include spontaneous recovery). Disease progress on the other hand is a description of the disease and its response to treatment. In the context of simulation and modeling, it is useful to think of clinical pharmacology as a model itself, i.e., the combination of disease progression and drug action. The purpose of the “Impact” series is to foster the use of M&S activities in all phases of drug development by illustrating the advantages and enhancing the applicability of M&S in product discovery, development, and marketing programs. The series is intended for drug development project team members from discovery to phase 4 clinical trials. This includes pharmacologists, ADME scientists, PK/PD modelers, clinical pharmacologists, clinical development team members, regulatory affairs specialists, and other interested professionals. Register for this free webinar at www.rosaandco.com/webinar. After registering you will receive a confirmation email containing information about joining the webinar. More information about the webinar series, an archive of past webinars, and a list of future webinar speakers may be found at www.rosaandco.com/webinar. Please allow 5-10 minutes for a Java applet to be installed on your computer prior to joining our webinar series for the first time. Toufigh Gordi, PhD President, PK/PD and Clinical Pharmacology Services Rosa & Co. LLC: www.rosaandco.com E-mail: [email protected] Tel.: 408-480-7314 Fax: 408-370-9810 The information contained in this e-mail message, e-mail message sequence, and/or any enclosures is confidential, and it may be privileged and protected from unauthorized use and/or disclosure. If you are not the intended recipient, any use, dissemination, distribution, or copying is strictly prohibited. If you received this e-mail in error, PLEASE NOTIFY THE SENDER immediately and destroy this message, any enclosures, and any copies of the message and/or the enclosures. Thank you.
