Dear Rob,

There are a couple of steps you need to perform to prepare your computer's 
folder structure - in your case, it looks like /opt does not exist. Create it 
using 

sudo mkdir /opt

and set appropriate permissions using

sudo chown -R <username> /opt

(where <username> is your username, without brackets) before finally running 
SETUP72 as you had it. That should fix the issue.

If you install MPICH2 for parallel NONMEM execution, I would be very interested 
in your experiences (as well as those of any others who've tried it). We have 
had some odd problems using it under Mac OS X (mainly, non-reproducible results 
with numerically complex models), although it seems to work fine under the 
Windows and Linux systems we tested with the same compiler (Intel Visual 
Fortran). We saw the issue with a range of different compiler switches.

Best
Justin

On Oct 23, 2011, at 5:24 PM, Rob ter Heine wrote:

> Dear NMUSERS,
> 
> I am trying to install NM7.2 on my macbook with OSX 10.7 lion installed. I 
> installed gfortran from this URL 
> http://gcc.gnu.org/wiki/GFortranBinaries#MacOS
> 
> I then tried installing OSX as described in the PDF readme on the 
> installation cd, but couldn’t really figure it out. My NM 7.2 CD is in the 
> /Volumes/NONMEM_7.2.0 directory. When executing the installation command I 
> get the error message as pasted from my terminal window below and the 
> installation halts. Any feedback on what I’m doing wrong and getting NM7.2 
> installed is appreciated.
> 
> Cheers!
> 
> Rob ter Heine
> 
> ----
> 
> MacBook-van-Rob-ter-Heine:NONMEM_7.2.0 robterheine$ /bin/bash SETUP72 
> /Volumes/NONMEM_7.2.0 /opt/nm72 gfortran y ar same rec i
> NONMEM 7.2.0 INSTALLATION UTILITY - UNIX Bourne-Again SHell version
> For instructions, see readme_7.2.0.pdf or readme_7.2.0.txt on the CD
>  
> SETUP72 /Volumes/NONMEM_7.2.0 /opt/nm72 gfortran y ar same rec i default 
> nonmem72e.zip nonmem72r.zip
> CD-ROM drive is /Volumes/NONMEM_7.2.0
> NONMEM 7.2 directory is /opt/nm72
> Command for FORTRAN compiles is gfortran
> Optimization for Fortran compiles is y
> Command to build NONMEM archive is ar
> Sizes is same (SIZES.f90 is always used)
> Recompile is rec
>  All binaries will be recompiled
> Interactive is i
> Unzip program is unzip
> Encrypted source file is nonmem72e.zip
> Unencrypted file is nonmem72r.zip
>  
> To learn how to override the defaults, enter
> % SETUP72 help
>  
> Continue (y/n) [y]?y
>  
> The directory /opt/nm72 does not exist.
> Step 1. Creating /opt/nm72
> mkdir: /opt: No such file or directory
> Cannot create /opt/nm72
> De informatie in dit e-mail bericht is uitsluitend bestemd
> voor de geadresseerde. Verstrekking aan en gebruik door
> anderen is niet toegestaan. Door de elektronische verzending
> van het bericht kunnen er geen rechten worden ontleend aan de
> informatie.

--

Justin Wilkins, PhD

Exprimo NV

Tel:    +41 (0) 81 599 23 82
Mobile: +41 (0) 76 561 09 49
E-mail: justin.wilk...@exprimo.com
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