Dear Yi,
For the simple model you outline here, NONMEM might not be the most efficient tool to use. A simple survival model like that can done in R with one line of code. Kind regards, Filip From: [email protected] [mailto:[email protected]] On Behalf Of yi liu Sent: Thursday, 3 November 2011 15:36 To: [email protected] Subject: [NMusers] How to do parametric survival modeling Hi, I am not very familiar with NONMEM, but need to use NONMEM to do parametric survival modeling. Can someone give me a simple example of how to do the following with loglogistic distribution? log(Y_i)=mu+ theta_1*X_{1i}+theta_2*X_{2i} +sigma*Z_i where Y_i is the survival time for ith subject mu is the intercept term X_{1i} is the age for ith subject X_{2i} is sex for the ith subject sigma is the standard deviation for the error term Z_i Z_i is the random error term with standard logistic distribution If you have something similar or any other suggestions, that would be greatly appreciated too! Thanks a lot!
