Is this a simulation run? May be residual error? I never seen integration problem to result in incorrect profiles. Also check the data file, may be extra dose was given? Leonid
> On Nov 2, 2013, at 8:01 PM, [email protected] wrote: > > Hello NONMEM Users, > > NONMEM outputs for few subjects look strange. Some subjects have 2 Cmax > (IPRED) after a single SC dose. One Cmax looks normal. Another one is a > smaller bump before the normal Cmax. Otherwise, the problem runs OK. Can it > be an integration error? I use ADVAN13. > > Thank you, > Pavel
