Dear Colleagues, It is a pleasure to invite you to the fourth meeting of Pharmacometrics Network Benelux.
Please mark the following date and time in your agenda: When: Wednesday, April 9th 2014 - 12:00 - 18:00 Where: GRÜNENTHAL GMBH, Corporate Center, Zieglerstr. 1, 52078 Aachen, Germany. Main contact number: +49 241 569 0 Agenda theme: Adaptive features in drug evaluation and use - methodological and practical considerations You can already register by sending an e-mail to [email protected]<mailto:[email protected]>. IF YOU WISH TO ATTEND, PLEASE MAKE SURE YOU REGISTER AT THE E_MAIL ADDRESS PROVIDED ABOVE. The meeting will include a light lunch, a coffee/tea break and drinks upon closure. SCIENTIFIC PROGRAM: 12.30 - 1.30 pm Lunch 1.30 – 1.35 pm Welcome Dr. Roberta Bursi, Head Pharmacometrics GRT 1.35 – 1.45 pm Global Biometrics at GRT. Mrs. Anne Danniau, MSc, SVP Global Biometrics GRT 1.45 – 2.45 pm Flexible design strategies for clinical trials: Methods and applications. Prof. Tim Friede, Gottingen University, Germany 2.45 – 3.15 pm Practical Considerations for Bayesian Adaptive Design Implementation Dr. Benoît Beck, Axiosis sprl, Charleroi, Belgium 3.15 – 3.45 pm Dose Response Modeling with Flexible Dose Designs – A case example. Dr. An Vermeulen, Janssen Pharmaceutica, Beerse, Belgium 3.45 – 4.00 pm Coffee break 4.00 – 4.30 pm Bayesian Adaptive Sampling Time Design under constraints to permit prediction. Bruno Boulanger, CSO, Arlenda S.A., Belgium 4.30 – 5.00 pm Bayesian Adaptive Dose Finding Procedure (First-in-Human Trial in Traumatic Brain Injury). Mrs. Iva Kezic, MSc, Janssen Pharmaceutica, Beerse, Belgium 5.00 – 5.30 pm Non-futility assessment in an adaptive-design dose-ranging studies ? Application to oral factor Xa inhibitors for thromboprophylaxis after total knee replacement surgery. Dr. Eugene Cox, Quantitative Solutions, Breda, The Netherlands 5.30 – 5.35 pm Closure 5.35 – 6.30 pm Drinks & … Venue There will be a security check when arriving at the Grünenthal Corporate Center (ID required) and participant will receive a badge. Parking will be possible at the long term parking facility. (Walking distance from the Corporate Center. Please). Coming by air the nearest airports are Cologne and Düsseldorf. Trains from both airports to Aachen Hauptbahnhof are leaving regularly approximately every 40 Minutes, duration around 1h35min (www.bahn.de<http://www.bahn.de>). Taxi from Aachen Hauptbahnhof to Grünenthal GmbH takes 15 Minutes, costs around 16 euros. We hope to see you in Aachen on April 9th! Anne Brochot Eugène Cox Rik de Greef Charlotte van Kesteren Thomas Kerbusch Catherijne Knibbe Ron Mathôt Stefaan Rossenu An Vermeulen Roberta Bursi On Pharmacometrics Network Benelux: the initiative aims to connect pharmacometricians in the Benelux (Belgium, Netherlands, and Luxembourg). The intention is to create an informal platform for the pharmacometric community in this region of the world (in industry, academia, hospital pharmacies as well as regulatory bodies), with the goal to promote professional and scientific awareness and interactions. Stay tuned on our latest activity by joining our group on LinkedIn. Shaonan [email protected]<mailto:[email protected]> Vorsitzender des Aufsichtsrates: Dr. Wilhelm Moll Geschäftsführer: Prof. Dr. Eric-Paul Pâques (Vorsitzender), Dipl.-Kfm. Stefan Genten, Dott. Alberto Grua, Dr. Klaus-Dieter Langner Sitz der Gesellschaft: Aachen. Registergericht: Amtsgericht Aachen, HRB Nr. 3546 Ust.-ID (VAT): DE 121737755 St.Nr. 201/5937/2986 Lieferanschrift: Zieglerstraße 6, 52078 Aachen, Tel.: +49 241 569-0, Fax: +49 241 569-1502 Korrespondenz: Grünenthal GmbH, 52099 Aachen, Deutschland www.grunenthal.com<http://www.grunenthal.com/>
