Hi Xyan, It will be very helpful if you could post your simulation code..
Best Mukul Minocha Clinical Pharmacology|Pharmacometrics AbbVie > On 20-Jun-2014, at 8:16, xyan4 <[email protected]> wrote: > > Dr. Bauer, Thanks for the reply. The error message still shows up when I put > $OMEGA right before $PK. Xiaoyu > > > > >> On 06/19/2014 11:17 pm, Bauer, Robert wrote: >> Make sure ALL your $OMEGA records are placed just before $PK >> Robert J. Bauer, Ph.D. >> Vice President, Pharmacometrics, R&D >> ICON Development Solutions >> 7740 Milestone Parkway >> Suite 150 >> Hanover, MD 21076 >> Tel: (215) 616-6428 >> Mob: (925) 286-0769 >> Email: [email protected] >> Web: www.iconplc.com [1] >> -----Original Message----- >> From: [email protected] >> [mailto:[email protected]] On Behalf Of xyan4 >> Sent: Thursday, June 19, 2014 10:32 PM >> To: [email protected] >> Subject: [NMusers] Compartment amounts, A(n), used as right hand side >> quantities in $PK >> Dear NMusers, >> I am doing a simulation in NONMEM 7.2.0. I have an amount compartment >> A(2) on the right-hand side bioavailability F2 in $PK. I got an error >> messages as “… 555 WITH A(I), $OMEGA FOR ETAS IN $PK (OR $MSFI >> NPOP=N) MUST PRECEDE $PK”. In the control file, $OMEGA actually >> precede $PK. The thing is that the same simulation worked in NONMEM 6. >> It seems that the feature that “Compartment amounts, A(n), can be >> used as right hand side quantities in $PK……” has been >> implemented since NONMEM 6, see slide 16 in >> http://www.cognigencorp.com/ecpag_org/2006/1_TomLudden_NONMEM_VI.pdf >> [2] >> I wonder what could cause this error in NONMEM 7.2, but not in NONMEM >> 6 and how I can solve this in version 7.2. >> Thanks for considering help! >> Xiaoyu >> ICON plc made the following annotations. >> ------------------------------------------------------------------------------ >> This e-mail transmission may contain confidential or legally >> privileged information that is intended only for the individual or >> entity named in the e-mail address. If you are not the intended >> recipient, you are hereby notified that any disclosure, copying, >> distribution, or reliance upon the contents of this e-mail is strictly >> prohibited. If you have received this e-mail transmission in error, >> please reply to the sender, so that ICON plc can arrange for proper >> delivery, and then please delete the message. >> Thank You, >> ICON plc >> South County Business Park >> Leopardstown >> Dublin 18 >> Ireland >> Registered number: 145835 >> Links: >> ------ >> [1] http://www.iconplc.com >> [2] http://www.cognigencorp.com/ecpag_org/2006/1_TomLudden_NONMEM_VI.pdf
