All,

Devin Pastoor is right. I can add that PsN-4.4.0 takes care of the label change automatically.

Best regards,
Kajsa Harling


On 05/01/2015 06:10 PM, Devin Pastoor wrote:
Dear Amir,

I believe this occurs when you have multiple values with the same (commented) label.

Eg

$Theta
...
(0, 10) ; [P] cov_cl
(0, 1.2) ; [P] cov_cl
...

In your case specifically you may have two with the label "[P]_" therefore just adding an additional character to either of those should resolve the issue.


Devin Pastoor
Center for Translational Medicine
University of Maryland, Baltimore

On Fri, May 1, 2015 at 12:00 PM Amir Youssef <[email protected]> wrote:
Dear all,

I am running the SCM tool in PsN but I am getting the following error: "Multiple instances of label [P]_ in problem to update, ambiguous parameter matching by label. at C:\Perl64\site\lib/PsN_4_2_0/model.pm line 3424."

This is a 2 compartment model with oral absorption (ADVAN 4) parameterized in CL and Q (i.e.: TRANS 4) with lag time. Here is the scm config file:

model=125_COV.ctl
directory=scm-both-125
search_direction=both
_only_successful_=1
parallel_states=1
p_forward=0.05
p_backward=0.01
continuous_covariates=WTKG,HTCM,BMIKGM2,AGEYR,TBILIUM,ASTUL,ALTUL,GGTUL,ALPUL,CRUM,BUNMM,UACUM,UPGL,ECRCL
categorical_covariates=SEXF
do_not_drop=WTKG,HTCM,BMIKGM2,AGEYR,TBILIUM,ASTUL,ALTUL,GGTUL,ALPUL,CRUM,BUNMM,UACUM,UPGL,ECRCL,SEXF
missing_data_token=-99
linearize=0
nm_version=default
retries=2
threads=4

[test_relations]
CL= SEXF,WTKG,HTCM,BMIKGM2,AGEYR,TBILIUM,ASTUL,ALTUL,GGTUL,ALPUL,CRUM,BUNMM,UACUM,UPGL,ECRCL
V2= SEXF,WTKG,HTCM,BMIKGM2,AGEYR,TBILIUM,ASTUL,ALTUL,GGTUL,ALPUL,CRUM,BUNMM,UACUM,UPGL,ECRCL

[valid_states]
continuous = 1,5
catagorical=1,2


Many thanks in advance for your help.


Amir

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Kajsa Harling, PhD
System Developer
Department of Pharmaceutical Biosciences
Uppsala University

[email protected]
+46-(0)18-471 4308

http://www.farmbio.uu.se/research/researchgroups/pharmacometrics/
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