Hi,
Sam is using WFN.
WFN adds -prdefault by default to the command line. This speeds up
typical use of NONMEM by avoiding recompilation.
The default behaviour is changed by unsetting the environment variable
args7:
set args7=
This will then allow WFN users to use $SIZES.
Best wishes,
Nick
On 18/06/2015 12:42 a.m., Sam Liao wrote:
Dear Robert,
I did not have –prdefault anywhere in my command.
Best regards,
Sam Liao
Pharmax Research Inc.
14 Upland,
Irvine, CA 92602
Phone: 201-9882043
efax: 720-2946783
www.pharmaxresearch.com
On 6/17/2015 2:21 PM, Bauer, Robert wrote:
Do not add –prdefault on your command line.
Robert J. Bauer, Ph.D.
Vice President, Pharmacometrics R&D
ICON Early Phase
Office: (215) 616-6428
Mobile: (925) 286-0769
[email protected] <mailto:[email protected]>
www.iconplc.com <http://www.iconplc.com>
*From:*[email protected]
[mailto:[email protected]] *On Behalf Of *Sam Liao
*Sent:* Wednesday, June 17, 2015 1:36 PM
*To:* [email protected]
*Subject:* [NMusers] $SIZES failed
Hi,
My PK model has 42 theta and 35 omega exceeding the default limits.
When I used $SIZE to change these size in my control file, I still get
the error msg from nmtran.exe
"MAY NOT USE -prdefault: LVR IN SIZES.f90 WOULD NEED TO BE INCREASED
TO 35"
Is there way to get around this problem? Somehow, the $SIZE statement in
the control stream was ignored.
--
Sam Liao
Pharmax Research Inc.
14 Upland,
Irvine, CA 92602
Phone: 201-9882043
efax: 720-2946783
www.pharmaxresearch.com <http://www.pharmaxresearch.com>
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--
Sam Liao
Pharmax Research Inc.
14 Upland,
Irvine, CA 92602
Phone: 201-9882043
efax: 720-2946783
www.pharmaxresearch.com
--
Nick Holford, Professor Clinical Pharmacology
Dept Pharmacology & Clinical Pharmacology, Bldg 503 Room 302A
University of Auckland,85 Park Rd,Private Bag 92019,Auckland,New Zealand
office:+64(9)923-6730 mobile:NZ+64(21)46 23 53 FR+33(7)80 48 55 50
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Holford SD, Allegaert K, Anderson BJ, Kukanich B, Sousa AB, Steinman A, Pypendop,
B., Mehvar, R., Giorgi, M., Holford,N.H.G. Parent-metabolite pharmacokinetic models
- tests of assumptions and predictions. Journal of Pharmacology & Clinical
Toxicology. 2014;2(2):1023-34.
Holford N. Clinical pharmacology = disease progression + drug action. Br J Clin
Pharmacol. 2015;79(1):18-27.
