Dear Ana, If you only want to consider covariance between 3 parameters, I suggest you put these three in an $OMEGA BLOCK(3) and list the remaining OMEGAs separately outside the block.
Best, Elke -----Original Message----- From: [email protected] [mailto:[email protected]] On Behalf Of Ana Miranda Bastos Sent: Tuesday, July 28, 2015 2:52 PM To: [email protected] Subject: [NMusers] Implementation of the OMEGA covariance matrix Dear NMusers, I wonder if someone could help me to implement the OMEGA covariance matrix below. $OMEGA 0.09 ; PPV_VMAX 0.00 0.09 ; PPV_V1 0.00 0.00 0.09 ; PPV_V2 0.00 0.00 0.00 0.09 ; PPV_KD 0.00 0.01 0.00 0.00 0.09 ; PPV_BMAX 0.00 0.01 0.00 0.00 0.01 0.09 ; PPV KM I don't want to fix any value to zero, but I don't know how to better illustrate that I would like to consider a covariance between: . V1 and Bmax . Bmax and Km . V1 and Km Any advice is highly appreciated. Thank you in advance. Kind regards, Ana ------------------------------------------ Ana Bastos, Pharm, MSc, PhD student Pharmacologie cellulaire et moléculaire (Cellular and Molecular Pharmacology Unit) Louvain Drug Research Institute Université catholique de Louvain (Catholic University of Louvain) UCL 7370 avenue E. Mounier 73 1200 Bruxelles, Belgique ------------------------------------------ http://www.facm.ucl.ac.be
