All over the world, Pfizer colleagues are working together to positively impact 
health for everyone, everywhere. Each position at Pfizer touches and 
contributes to the success of our business and our world. That's why, as one of 
the global leaders in the biopharmaceutical industry, Pfizer is committed to 
seeking out inspired new talent who share our core values and mission of making 
the world a healthier place.

Job Summary

A Systems Pharmacology Modeler position at the Principal Scientist level is 
available in the Translational Modeling and Simulation group within 
Pharmacokinetics, Dynamics and Metabolism (PDM) New Biologic Entities (NBE). 
The successful applicant will apply state-of-the-art modeling and simulation 
methods to preclinical studies that enable key drug discovery decisions from 
early discovery stages to the first-in-human study. As a member of 
multidisciplinary project teams, the candidate will develop and implement 
quantitative systems pharmacology and mechanism-based PK-PD models which impact 
the quality of decisions regarding target prioritization, therapeutic modality 
selection, biomarker characterization, chemical, biotherapeutic optimization 
and early clinical trial design. The individual will have an opportunity to 
support a wide range of projects, largely, but not exclusively, in the Oncology 
therapeutic area, covering small molecules and biotherapeutic modalities.

Education & Training

This individual should hold a Ph.D. or equivalent degree in systems biology, 
pharmacometrics, pharmaceutical sciences, (bio)engineering, mathematics or 
similar disciplines where modeling and simulation is emphasized, and 2+ years 
of academic or industrial experience in practical applications of systems 
pharmacology modeling and simulation. In particular, extensive experience in 
the areas of systems pharmacology/biology and/or mechanistic PK-PD modeling is 
required.

Equal Employment Opportunity

Pfizer is committed to equal opportunity in the terms and conditions of 
employment for all employees and job applicants without regard to race, color, 
religion, sex, sexual orientation, age, gender identity or gender expression, 
national origin, disability or veteran status. Pfizer also complies with all 
applicable national, state and local laws governing nondiscrimination in 
employment as well as work authorization and employment eligibility 
verification requirements of the Immigration and Nationality Act and IRCA. 
Pfizer is an E-Verify employer.

How to Apply

To learn more about this exciting opportunity, please visit 
http://www.pfizercareers.com. Search for job ID 1019241 and submit your 
application online.



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