WRT bootstrap, it makes much more sense to simply bootstrap the many nonmem runs (start 8 NONMEM runs at at time, rather than 1 run parallelized to 8 cores).
So, no, don't use parallel NONMEM for bootstrap, run multiple bootstrap samples at the same time. Mark Mark Sale M.D. Vice President, Modeling and Simulation Nuventra, Inc. (tm) 2525 Meridian Parkway, Suite 280 Research Triangle Park, NC 27713 Office (919)-973-0383 [email protected]<[email protected]> www.nuventra.com<http://www.nuventra.com> Empower your Pipeline CONFIDENTIALITY NOTICE The information in this transmittal (including attachments, if any) may be privileged and confidential and is intended only for the recipient(s) listed above. Any review, use, disclosure, distribution or copying of this transmittal, in any form, is prohibited except by or on behalf of the intended recipient(s). If you have received this transmittal in error, please notify me immediately by reply email and destroy all copies of the transmittal. ________________________________ From: [email protected] <[email protected]> on behalf of Pavel Belo <[email protected]> Sent: Tuesday, December 8, 2015 4:54 PM To: [email protected] Subject: [NMusers] setup of parallel processing and supporting software - help wanted Hello The Team, We hear different opinions about effectiveness of parallel processing with NONMEM from very helpful to less helpful. It can be task dependent. How useful is it in phase 3 for basic and covariate models, as well as for bootstrapping? We reached a non-exploratory (production) point when popPK is on a critical path and sophisticated but slow home-made utilities may be insufficient. Are there efficient/quick companies/institutions, which setup parallel processing, supporting software and, possibly, some other utilities (cloud computing, ...)? A group which used to helped us a while ago disappeared somewhere... Thanks, Pavel
