Hi All,
I would be most grateful for any assistance with the following issues with 
NONMEM. I'm using a mac (2012) and I've just recently upgraded to yosemite. The 
problem is that NONMEM has stopped running on my laptop since upgrading. This 
is fairly typical after an upgrade in mac and is usually a problem with 
gfortran compatibility which should normally be resolved by uninstalling and 
re-installing gfortran with the following command:
sudo rm -r/usr/local/gfortran/usr/local/bin/gfortran
I've tried re-installing the 5.2 version of gfortran which is compatible with 
yosemite (https://gcc.gnu.org/wiki/GFortranBinaries#MacOS).
I then tried running NONMEM but I'm getting the following errors:








   WARNINGS AND ERRORS (IF ANY) FOR PROBLEM    1              (WARNING  2) 
NM-TRAN INFERS THAT THE DATA ARE POPULATION.              (WARNING  13) WITH 
USER-WRITTEN PRED OR $PRED, NM-TRAN CANNOT APPEND THE MDV DATA ITEM.Note: The 
following floating-point exceptions are signalling: IEEE_INVALID_FLAG 
IEEE_DIVIDE_BY_ZERORecompiling certain componentsMUMODEL.f90:67:10:
       USE FSIZES,       ONLY: F_PC,F_PG,F_LVO,F_LVS          1Fatal Error: 
Cannot read module file ‘fsizes.mod’ opened at (1), because it was created by a 
different version of GNU Fortrancompilation terminated.PRPNM.f90:58:10:
       USE PNM_CONFIG,  ONLY: PNM_UPAR,M_IDEFD,M_IDEFA,M_EL,M_TQ,M_DAC,M_DPC    
       1Fatal Error: Cannot read module file ‘pnm_config.mod’ opened at (1), 
because it was created by a different version of GNU Fortrancompilation 
terminated.Building NONMEM Executablegfortran: error: temp_dir/MUMODEL.o: No 
such file or directorygfortran: error: temp_dir/PRPNM.o: No such file or 
directory































No nonmem execution.
It appears there are still problems with gfortran. Would anyone be kind enough 
to assist?
My other question: Is there a way to prevent future upgrades on the mac 
interfering with NONMEM?
Kind Regards,
AdedejiPhD student, UCL.                                          

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