Thanks Brian; it worked with NOINTERACTION . -Varun 

    On Friday, January 13, 2017 11:32 AM, "Sadler, Brian" 
<brian.sad...@iconplc.com> wrote:
 

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{}#yiv2347518706 Hi Varun,    You might try explicitly using “NOINTERACTION” 
with SAEM and IMP.    Cheers… Brian    From: owner-nmus...@globomaxnm.com 
[mailto:owner-nmus...@globomaxnm.com]On Behalf Of varun goel
Sent: Friday, January 13, 2017 9:55 AM
To: nmusers@globomaxnm.com
Subject: [NMusers] Error with SAEM and LIKE Option    Dear All,  I get error 
while using SAEM estimation method for repeated time to event model. But, the 
same model runs well with LAPLACE. Could you suggest what I am missing below.   
  This $EST runs well $ESTIMATION MAXEVAL=999 METHOD=COND LAPLACE LIKE PRINT=1  
  Following $EST method fails with the following error  $EST METHOD=SAEM LAP 
LIKE NBURN=1000 NITER=1000 PRINT=200 IACCEPT=0.2 CTYPE=3  CINTERVAL=10  $EST 
METHOD=IMP LAPLACE CTYPE=3 CINTERVAL=1 NITER=300  IACCEPT=0.2 DF=6 SEED=123    
Error  (WARNING  121) INTERACTION IS IMPLIED WITH EM/BAYES ESTIMATION METHODS   
 AN ERROR WAS FOUND IN THE CONTROL STATEMENTS.    545  $ESTIM: "INTERACTION" 
CANNOT BE USED WITH "LIKE" OR "-2LL".    Varun  
 
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