Summer Internship Alnylam was founded in 2002 on a revolutionaryvision and bold mission which remain firmly in place today. We are leading thetranslation of RNAi as a new class of medicines with a core focus on RNAitherapeutics toward genetically defined targets for the treatment of serious,life-threatening diseases with limited treatment options for patients and theircaregivers. In January 2015, we announced our “Alnylam 2020” guidance thatreflects our expected transition from a late-stage clinical development companyto a multi-product commercial-stage company with a sustainable developmentpipeline. Alnylam is proud to have been recognized as one of The Boston Globe’sTop Places to Work in 2015 and 2016.
Overview of the Program: With RNAi technology, wehave the opportunity to treat disease and impact the lives of patients in afundamentally new way. Alnylam Summer Internships are designed to developpractical biotech industry knowledge and soft skill advancement, whilecontributing to the company’s overall mission and goals. Internswill also participate in company wide functions such as Annual Community ServiceDay, Summer Outing, as well as events & development programs designedexclusively for these students. Summerintern position in the Clinical Pharmacology & Pharmacometrics group. Job Description: Through this program, intern will gain experience in utility of quantitativemethods in supporting RNAi therapeutics for drug development of orphan diseaseindications. The students may interact with clinicians, biometrics, research,DMPK, or clinical pharmacology scientists. Depending on the interests ofthe interns following projects may be assigned · Compartmentaland PBPK modeling of RNAi therapeutics · Exposure-responsemodeling · Systemspharmacology modeling of diseaseusing literature and in-house data · Statisticalmodeling of endpoints informing trial operating characteristics Requirements: Strong understanding of fundamentalsof PKPD and hierarchical modeling of continuous and non-continuousendpoints. Proficiency with quantitative software e.g. Phoenix, R, and NONMEM.Exposure to Bayesian approaches is highly desirable. Currentlyenrolled in a PhD degree program in Pharmacometrics, Pharmaceutical Sciences,Bioengineering, Applied Mathematics/Statistics, or a related field. Eligible to work on afull-time basis during the internship duration. Please visit the following linkto apply https://alnylam.taleo.net/careersection/alny_ext/jobdetail.ftl?job=IN.17.0001
