Dear NMusers, Maybe a simple question. I was wondering if there is such functionality in NONMEM to inherit the past (e.g. previous row) value of parameter calculated with time varying covariates? For instance, the CL was determined by a time varying covariate. Calculation CL was a negative number in time record 3 due to the covariate value at that time point. I would like to use calculation CL in time record 2 as instead for time record 3. Pseudocode is somewhat like 'IF (CL[i].LE.0) CL[i]=CL[i-1]'. Is this possible to implement within NONMEM? Thanks in advance.
Warm regards, Tingjie Tingjie Guo I Trainee Research Assistant Academic Medical Centre, University of Amsterdam. VU University Medical Centre, Vrije University Amsterdam. Room ZH-7D-172, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands. Email: [email protected]<mailto:[email protected]> / [email protected]<mailto:[email protected]> Mobile: +31 659738693
