How to Ensure Your QSP Model is Useful - Illustrative Examples and Lessons Learned
Christina Friedrich, PhD and Mike Reed, PhD Chief Engineer and Chief Scientist, Rosa & Co. Wednesday, April 25, 2018, 12:00 pm to 1:00 pm EST Register at https://www.rosaandco.com/webinars Abstract: Quantitative Systems Pharmacology (QSP) modeling considers drug mechanism of action in the context of biological disease mechanisms to improve understanding of human biology and pharmacology. QSP models differ from PK/PD models in their purpose and data requirements, and there can be significant variability among QSP models in scope and level of detail, research questions addressed, and available data. If all models are wrong, but some are useful, how can you make sure that your QSP model is as useful as possible? In this Webinar, we address some common missteps and inefficiencies in mechanistic QSP modeling that can reduce the usefulness of a model. We will draw on illustrative examples from personal experience and the public domain to illustrate relevant aspects of modeling approach and model quality and summarize lessons learned for ensuring that QSP models are as useful as possible.