Dear Colleagues, International Society of Pharmacometrics will host a webinar on Friday, January 18, 2019 @12:30 EST. The webinar titled, "Delay Differential Equations Based Models in NONMEM", will be hosted by Wojciech Krzyzanski, PhD, University at Buffalo. Models using delay differential equations (DDEs) are getting increasingly popular in analysis of data exhibiting delays. Many pharmacometric software support DDE solvers to facilitate DDE based model development. Recently, an advanced DDE solver for stiff differential equations has been implemented in a pre-release version of NONMEM as ADVAN 16. The objective of this presentation is to introduce basic concepts underlying DDE based models and show how they can be developed using ADVAN16. Outline: -Examples of PKPD systems with delays -Pharmacomatric software supporting DDE solvers -RADAR5 -Introduction to ADVAN16 -Simulation: rheumatoid arthritis model -Individual parameter estimation: tumor growth inhibition model -Population parameter estimation: model of erythropoietin effect on RBCs -Questions and answers
Please use the link below to view additional details and to register for this free event. Registration is required to view this event. https://zoom.us/webinar/register/WN_SRpxQl3dRKCTI_uhb_b44g Regards, Wojciech Krzyzanski
