Dear All We are running our next ‘Intensive 5-day Workshop on Model-Informed Drug Development’ in Krakow, Poland, 13-17 May 2019.
Delegates will learn a range of topics including: - Metabolic drug clearance (CL) - Metabolic drug-drug interactions (DDIs) - Gut first-pass metabolism - Oral drug absorption incorporating food effects and the impact of dosage form - Effect of transporters and enterohepatic recirculation on kinetics and DDIs - Drug distribution to different organs - Population variability in drug concentration-time profiles - Variation in kinetics in specific populations (pediatrics, ethnic groups, various disease populations) - Modeling of therapeutic proteins - Pharmacodynamic effects of different compounds - Time-course of drug in plasma that fits observed clinical data (achieved by combining fitting techniques with IVIVE, PBPK and drug-specific in vitro data) *For more information please visit: * *https://www.certara.com/wp-content/uploads/Resources/Workshops/FL_SimcypWorkshop-KrakowA2019.pdf* <https://www.certara.com/wp-content/uploads/Resources/Workshops/FL_SimcypWorkshop-KrakowA2019.pdf> Regards Masoud
