We are happy to share with you the programme of the 15th meeting of the 
Pharmacometrics Network Benelux (PNB)



The PNB initiative aims to connect pharmacometricians in the Benelux (Belgium, 
Netherlands, and Luxembourg). The intention is to create an informal platform 
for the pharmacometrics community in this region of the world (in industry, 
academia, hospital pharmacies as well as regulatory bodies), with the goal to 
promote professional and scientific awareness and interactions.



The 2019 Fall meeting will be held Thursday, November 28th 2019 at Het Nieuwe 
Instituut, Museumpark 25, 3015 CB, Rotterdam, The Netherlands.



The meeting is free of charge, but registration is required before November 
20th  via 
http://www.123formbuilder.com/form-5089455/pnb-registration-autumn2019<https://eur01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.123formbuilder.com%2Fform-5089455%2Fpnb-registration-autumn2019&data=02%7C01%7Cb.dewinter%40erasmusmc.nl%7Ce7794f5acf7642c98b5f08d75230cee1%7C526638ba6af34b0fa532a1a511f4ac80%7C0%7C0%7C637068241895067472&sdata=MGl%2BdHehdKxp6S20f5vGUTMeS8aGPz%2F2UMeHt%2BbhsjA%3D&reserved=0>


Pharmacometrics Network Benelux Fall Meeting 2019 - Thursday 28 November



Theme 'Immunomodulation'



12:00-13:00      Arrival and lunch



13:00-13:45     Gertjan Wolbink (Reade/Sanquin): Immuno-modulators impacting PK 
of immunogenic biologicals in rheumatology: evidence, mechanisms and clinical 
relevance

13:45-14:15     Sophie Berends (AmsterdamUMC): Tumor necrosis factor-mediated 
disposition of infliximab in ulcerative colitis patients

14:15-14:45     John Maringwa (Certara): Applications of model-based 
meta-analysis in psoriasis to support decision making



14:45-15:30     Coffee break



15:30-16:00     Louise Andrews (ErasmusMC): Tacrolimus - individualization of 
starting dose in solid organ transplant patients

16:00-16:30     Mendy ter Avest (Radboudumc): Pharmacometrics as a tool to 
improve treatment with eculizumab, a complement component C5-inhibitor

16:30-17:00     Brenda de Winter (ErasmusMC): Pharmacokinetics of 
immunoglobulin treatment in Guillain-Barré Syndrome



17:00-18:00     Closure and drinks



Meeting venue:
Het Nieuwe Instituut
Museumpark 25
3015 CB, Rotterdam
The Netherlands



This meeting will be locally hosted by Erasmus MC and is supported by InsightRX 
and ISoP.



Local Organizers:

Brenda de Winter

Birgit Koch



PNB Steering Committee:

Thomas Dorlo

Stefaan Rossenu

Sven van Dijkman

Pieter Colin

Anthe Zandvliet

Wilbert de Witte


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