Introduction course to Population PK and PK/PD modelling with NONMEM During this three days course, participants will be introduced to the basic principles of population approach nonlinear mixed effects modelling in pharmacokinetic (PK) and pharmacodynamic (PD) evaluation of drugs and will have opportunities for hands-on PK and PK/PD modelling and simulation examples relevant to drug development. Topics include how to work with NONMEM and R, data file preparation, model coding and visualization/interpretation of the results.
Target audience The course is intended for people who have a basic knowledge of PK, PD and data analysis, and wish to extend their knowledge and skills on PK/PD in drug development. Course objectives Aim of the course is to familiarize the participants with the basics of population PK/PD modelling and to train the participants in working with NONMEM to conduct population PK and PK/PD data analyses. Details Instructor Dr. Jasper Stevens Duration 3 x 8 hours Dates 6, 7 and 8 May 2020; 09:00-17:00 Location University Medical Center Groningen, Groningen, The Netherlands Language English Maximum capacity 16 participants Course overview Session 1 Introduction to population PK modelling, NONMEM and R Session 2 NONMEM work flow for population PK models; data management, data exploration, model code and execution, output and interpretation Session 3 Population PK models continued: alternative administration routes, solving differential equations using NONMEM and simulations Session 4 Population PK/PD models: introduction to PK/PD models and implementation of direct effect models in NONMEM Session 5 Population PK/PD models: effect compartment and indirect response models Course fee The course fee is 1200 EUR, including course materials, coffee breaks, lunches and one evening dinner (Wednesday evening). Computers are available, including the required software packages. A limited number of (PhD) students can register for a reduced fee (600 EUR), for which a support letter of the supervisor has to be included upon registration. Cancellation received before April 10th, 2020 is subject to full refund, cancellation received after this date is subject to 50% refund. Registration To register for the course, please send an email to non...@kff.umcg.nl<mailto:non...@kff.umcg.nl> requesting a registration form. ----------------------------------------------- Jasper Stevens, PhD University Medical Center Groningen Clinical Pharmacy and Pharmacology De Brug 50.1.D.15A; EB70 PO Box 30001 9700 RD Groningen Tel: +31 50 361 7875 Fax: +31 50 361 4087 ----------------------------------------------- ________________________________ De inhoud van dit bericht is vertrouwelijk en alleen bestemd voor de geadresseerde(n). Anderen dan de geadresseerde(n) mogen geen gebruik maken van dit bericht, het niet openbaar maken of op enige wijze verspreiden of vermenigvuldigen. Het UMCG kan niet aansprakelijk gesteld worden voor een incomplete aankomst of vertraging van dit verzonden bericht. The contents of this message are confidential and only intended for the eyes of the addressee(s). Others than the addressee(s) are not allowed to use this message, to make it public or to distribute or multiply this message in any way. The UMCG cannot be held responsible for incomplete reception or delay of this transferred message.
