Pfizer is recruiting a highly motivated postdoctoral candidate to develop and 
analyze mechanistic mathematical models that incorporate resistance mechanisms 
across patients and tumors, with the goal of improving predictions of 
therapeutic response for initial clinical trials. This Postdoctoral Fellowship 
is an opportunity to work within a dynamic Quantitative Systems Pharmacology 
group, who are at the forefront of the application of mechanistic systems 
models to address critical uncertainties in drug discovery and development.

The candidate will work within Pfizer 
Oncology<https://www.pfizer.com/science/oncology-cancer/research>, which is 
committed to discovering, investigating, and developing transformative 
therapies that improve the outlook for cancer patients worldwide. Our strong 
pipeline includes biologics, small molecules, immunotherapies, and biosimilars, 
and is centered on exploring a wide array of approaches across many tumor 
types. We seek to translate the most innovative science into meaningful 
breakthrough medicines that redefine life with cancer for patients.

In addition, Pfizer’s Postdoctoral Fellows pursue their research and career 
training in a culture steeped in the translation of basic science discovery 
into meaningful medicines for patients of all ages and geographies. 
Postdoctoral trainees are mentored in a setting that places a premium on your 
preparation for the next stage of your career whether it is a career in 
industry or academia.

The successful candidate will have earned a Ph.D. in Applied Mathematics, 
Engineering, Physics, Pharmaceutical Sciences, or other related discipline and 
has a demonstrated track record in scientific publication. The postdoctoral 
fellow will develop and analyze mathematical models of cancer resistance that 
integrate biological knowledge and available data from Pfizer’s preclinical and 
clinical programs, with the goal of providing tools for pre-clinical to 
clinical translation, dose selection, and clinical trial design. They will work 
collaboratively with biologists, clinicians, clinical pharmacologists, 
pharmacometricians, QSP and nonclinical modelers to improve designs for 
effective and durable oncology therapies.

For questions about this project or inquiries, please contact Mary Spilker 
([email protected]<mailto:[email protected]>) or Blerta Shtylla 
([email protected]<mailto:[email protected]>).

To apply follow this link 
here<https://pfizer.wd1.myworkdayjobs.com/PfizerCareers/job/United-States---California---La-Jolla/Postdoctoral-Research-Fellow--Quantitative-Systems-Pharmacology_4794485>
 
(https://pfizer.wd1.myworkdayjobs.com/PfizerCareers/job/United-States---California---La-Jolla/Postdoctoral-Research-Fellow--Quantitative-Systems-Pharmacology_4794485)


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