Tingjie:
We have corrected the quotation mark error, thank you for pointing it out.

Indrajit, our expert on Mac systems, has checked around several sites for a 
gfortran ARM build of version 10.  He has informed me of the following, perhaps 
it will help:

This 
https://developer.arm.com/tools-and-software/open-source-software/developer-tools/gnu-toolchain/gnu-rm/downloads
 website appears to have gcc compilers with ARM support. However, this is not 
among our two most tried and tested websites, which are  
https://github.com/fxcoudert/gfortran-for-macOS/releases  and  
http://hpc.sourceforge.net/<http://hpc.sourceforge.net/>  .

If installed using Homebrew, users need to find the exact version number from 
the aforementioned page. Then, go to Homebrew and submit "brew install 
[email protected]<mailto:[email protected]>" . "brew install gcc-arm-none-eabi-10.3" might work 
as well, although, I'm not 100% sure.

Right at this moment, "brew install gcc@10" might install 10.3 as well 
https://formulae.brew.sh/formula/gcc


Robert J. Bauer, Ph.D.
Senior Director
Pharmacometrics R&D
ICON Early Phase
820 W. Diamond Avenue
Suite 100
Gaithersburg, MD 20878
Office: (215) 616-6428
Mobile: (925) 286-0769
[email protected]<mailto:[email protected]>
www.iconplc.com<http://www.iconplc.com>

From: Tingjie Guo <[email protected]<mailto:[email protected]>>
Sent: Monday, November 1, 2021 10:55 AM
To: Bauer, Robert <[email protected]<mailto:[email protected]>>; 
NMusers <[email protected]<mailto:[email protected]>>
Subject: [EXTERNAL] Re: [NMusers] RE: Updated materials on NONMEM 7.5

Hi Bob,

There seems to be a single quotation mark ' missing at the end of line 336 in 
"SETUP75std".

I was wondering if there will be Apple silicon native support any time soon? 
You mentioned in the readme file that NONMEM now only works on  GCC10 or 
smaller on Macs. But I also realized that GCC@10 does not have a ARM binary 
build e.g. on brew or github. Hence it works non-natively through Rosetta 
translation on Apple silicon Macs.

Many thanks!

Warm regards,
Tingjie



On Mon, Oct 18, 2021, at 18:44, Bauer, Robert wrote:

Dear nmusers:

Earlier e-mail contained faulty link to MACOSX.  Please use the following links.



Please note several updated materials pertaining to the NONMEM software:



1)      An updated bug list nm750_bug_list.pdf in

In https://nonmem.iconplc.com/nonmem750<https://nonmem.iconplc.com/nonmem750>



2)      Updated installer for NONMEM7.5 for gfortran on Windows.  See 
README_NONMEM750_63gfortran463.txt, utilizing Microsoft MPI in

In https://nonmem.iconplc.com/nonmem750<https://nonmem.iconplc.com/nonmem750>



3)      Updated materials installing on Macs, see the readme files in

https://nonmem.iconplc.com/nonmem750/MACOSX<https://nonmem.iconplc.com/nonmem750/MACOSX>



4)      Updated materials on modeling stochastic differential equations

https://nonmem.iconplc.com/nonmem/sde_inline<https://nonmem.iconplc.com/nonmem/sde_inline>
 (see readme.txt)

https://nonmem.iconplc.com/nonmem/sde<https://nonmem.iconplc.com/nonmem/sde> 
(SDE_readme.docx)





Robert J. Bauer, Ph.D.

Senior Director

Pharmacometrics R&D

ICON Early Phase

820 W. Diamond Avenue

Suite 100

Gaithersburg, MD 20878

Office: (215) 616-6428

Mobile: (925) 286-0769

[email protected]<mailto:[email protected]>

www.iconplc.com<http://www.iconplc.com>




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