Dear all, The Centre for Human Drug Research (CHDR) in Leiden, the Netherlands, is looking for an ambitious (Senior) Pharmacometrician!
Who are we? CHDR is an independent institute specialising in innovative, early-stage clinical drug research (https://chdr.nl). CHDR conducts clinical research on new and existing drugs for pharmaceutical companies, but also initiates its own research. By combining cutting edge methods and technologies, state-of-the-art facilities, and talented researchers, we help maximise our clients’ success. We are located in Leiden, the Netherlands, and collaborate closely with Leiden University and the clinical departments of the Leiden University Medical Center. Job description As a pharmacometrician, you will join our Statistics & Pharmacometrics team. In this role you will be responsible for the independent coordination and execution of multiple complex pharmacokinetic (PK) and pharmacodynamic (PD) analyses of the clinical studies conducted at CHDR. Modelling projects will primarily be performed based on data from phase 1 studies with diverse pharmacodynamic outcome measures. You will have the opportunity to explore new scientific insights and innovative analysis methodologies, to collaborate on scientific publications and to guide research interns and PhD students in the field of pharmacometrics. Additionally, you will coordinate and execute concentration-QTc analyses as well as interim and final non-compartmental analyses (NCAs). You will communicate with different (internal) stakeholders, to inform them on the progress of your research and ensure that results are delivered within the agreed timelines. What are we looking for? We are looking for an experienced pharmacometrician. You have a PhD in PK-PD modelling, disease modelling and/or simulation in the context of drug research and development, confirmed with a track-record of peer-reviewed publications. Extensive experience with pharmacological/statistical software tools including R and NONMEM are required. Experience with WinNonLin is preferred. What do we offer you? You will join a dynamic, passionate organisation and will work within a small team in a multi-disciplinary environment. We offer a pleasant workplace with an open, multidisciplinary work environment. We also include good secondary employment conditions such as an end-of-year bonus, personal development opportunities and many social events. Application procedure If you are interested in this position, you can read more about the position online (https://chdr.nl/careers) or send an application with your CV and motivation letter to [email protected]. If you wish to receive more information, please don’t hesitate to reach out to me on LinkedIn or e-mail ([email protected]<mailto:[email protected]>) or send an email to Erica Klaassen, Team Leader Statistics and Pharmacometrics, via [email protected]<mailto:[email protected]>. Kind regards, Marije Otto Pharmacometrician Centre for Human Drug Research Zernikedreef 8, 2333 CL Leiden, The Netherlands +31 715246400 [email protected]<mailto:[email protected]> www.chdr.nl<http://www.chdr.nl>
