Dear NMusers,
We have an exciting postdoctoral position available in our Clinical
Pharmacy group at Freie Universitaet Berlin, focusing on forecasting the
evolution of antibiotic resistance. For more information, please see below.
Kind regards,
Linda
*Postdoctoral Research Fellow (m/f/d)*
We are an interdisciplinary, international, research group applying high
scientific standards and innovative methodologies with the ultimate aim
to foster the rational use of medicines while empowering young
scientists to perform clinically relevant research
(http://www.clinical-pharmacy.eu/ <http://www.clinical-pharmacy.eu/>).
Our group is affiliated with Freie Universitaet Berlin and situated in
an unique metropole that offers many exiting experiences.
Our research area, pharmacometrics and systems biology, is situated
within a transdisciplinary field and combines experimental and
theoretical concepts. Our research is based on two research pillars: (1)
Bioanalysis, microdialysis, cell culture, and (2) Pharmacometric (data)
analysis. As a key feature, we constantly bridge these two pillars. Our
pharmacometric projects are based on in vitro and/or in vivo data
obtained by experimental research, while innovative dynamic in vitro
systems utilise modelling and simulation approaches for optimising
experimental design. In addition, many of our projects are realised as
parts of clinical studies. Typically, our research is collaborative and
embedded in consortia at a national and international level (EU, global).
*Project summary*
As part of its second Grand Challenge Initiative, the Berlin University
Alliance is tackling the topic of global health. Global health combines
research and practice aiming to improve the health of all people
worldwide. The goal is to eliminate the existing inequalities in society
so that all people can lead healthy lives. Questions and challenges in
the field of global health concern not only the health sciences but also
a large number of other research areas such as law, environmental
science, the natural and social sciences, as well as politics, religion,
philosophy, material science, engineering, and communication studies.
With this in mind, the researchers of the Alliance partners who are
involved in the Grand Challenge Initiative on /Global Health/ are
adopting an interdisciplinary approach to investigate cross-cutting themes.
GlobalResist is one out of the four funded projects and aims to forecast
antibiotic resistance evolution as a novel approach to address a major
issue in global health. Development of resistance to antimicrobial
agents is one of the major challenges in the fight against infectious
diseases. GlobalResist is developing a wide-ranging approach to
predicting antibiotic resistance evolution that intricately links
different disciplines. The aim is to enable the assessment of risks of
patients developing resistance before use in the future, so that
resistance issues can ideally be avoided, and antibiotics can be used
more sustainably.
The GlobalResist project consortium involves the following Berlin
University Alliance partners: Freie Universität Berlin,
Charité-Universitätsmedizin Berlin, Technische Universität Berlin
*Vacancy and application*
We are looking for a full-time postdoctoral fellow in the field of
forecasting antibiotic resistance evolution by applying innovative
translational modelling and simulation techniques and/or in vitro
infection models to join our research group for a period of 2 years. To
be eligible for the positions, a PhD degree or equivalent is needed, as
well as a strong record in the research area of pharmacometric and/or in
vitro infection models and their data analysis. Additionally, experience
in either (i) evaluating pharmacokinetic, pharmacodynamic or systems
pharmacology data and pharmacometric analysis with NONMEM, R or similar
pharmacometric software, (ii) Bayesian analysis using STAN or similar
platforms, and bioinformatics, or (iii) one of our experimental
platforms (LC/MS-MS, microdialysis, bacterial infection models, in vitro
metabolism) is required. The position also offers supervision of PhD and
Master/Diploma students.
Applications in English should include a letter of motivation along with
a description of research interests and relevant qualifications for the
position. In addition, a curriculum vitae including a list of
publications and names/email addresses of 2-3 referees should be
provided. Please submit your application before the 24^th of April 2023
to:_charlotte.kloft@fu-berlin.de
<mailto:charlotte.kloft@fu%1f-berlin.de>_ and _linda.aulin@fu-berlin.de_
You can find the vacancy post here:
https://www.fu-berlin.de/universitaet/beruf-karriere/jobs/english/BC-GlobalResist-2023_engl.html
*Job profile*
* Contribution to the Berlin University Alliance project
“GlobalResist” (Consortium of seven different partners from three
different institutions)
* Performance and publication of research projects in pharmacometric
and translational modelling
* Contribution to conception and realisation of new research ideas and
collaborations
* General services in research (co-supervision of junior members;
IT/Cluster contact) and research organisation
*Qualification profile*
*Requirements:*
* Graduation in Pharmaceutical or Life sciences or related field
* Qualified PhD thesis in pharmacometrics, systems pharmacology, or
infection models, preferentially PK/PD modelling of antimicrobials
or antimicrobial resistance evolution
*Assets:*
1. Profound knowledge in pharmacometrics software: e.g. NONMEM/PsN,
Berkeley-Madonna, Monolix, nlmxR or similar
2. Good knowledge in the software programs R, PKSim, STAN, Pirana or
similar
3. Profound experience with or interest for in vitro work such as
bacterial infection models
4. In-depth experience in organisation and performance of research
projects and in scientific publication in the area of pharmacometrics
5. High intrinsic motivation/high level of commitment
6. Excellent team player
7. Strong verbal/written communication skills
8. Language skills: English excellent
Dr. Linda Aulin (she/her)
Postdoctoral Researcher
Freie Universität Berlin
Institute of Pharmacy
Dept. of Clinical Pharmacy & Biochemistry
Kelchstr. 31
12169 Berlin
Germany
Phone: + 49 30 838 50659
Fax: + 49 30 838 4 50656
Email: linda.au...@fu-berlin.de
www.clinical-pharmacy.eu
Twitter: @CPB_Kloft
LinkedIn: /company/cpb-kloft
