Please message me to learn more about this role at a growing precision oncology company:
Senior Director of Quantitative Pharmacology reports to the Head of Clinical Pharmacology and Toxicology and serves as an integral contributor to all the preclinical and clinical development projects at Company. Job duties & responsibilities: * Partner with Head of Clinical Pharmacology and Toxicology, Program Team leaders and R&D staff to lead the pharmacometrics and quantitative PK/PD strategy for Company's discovery and development programs * As a member of the Company's project teams, the individual will be responsible for applying model-based approaches to support compartmental and mechanism-based PK/PD analysis, evaluation of FIH dose and regimen recommendations. * Develop and execute strategies for mid-stage and late-stage Oncology programs to support regulatory questions and filings * Provide due-diligence and strategic regulatory advice/evaluations for oncology drug development programs * The successful incumbent will utilize a range of computational approaches (PK/PD, PBPK, pharmacometrics, systems-based, informatics). The scope of project responsibility will range from late discovery through registration. Required knowledge, skills, and experience: * A Ph.D. in Pharmacology, Biology, Engineering, Mathematics or related field with 10+ years of relevant experience in modeling and simulation. * Excellent understanding of PK (NCA, compartmental) and PK/PD principles. * Expertise in the application of Phoenix WinNonlin, PBPK related software, and R is required. * Experience with pharmacometrics with regulatory reporting is a plus. * Superior communication skills (both written and oral) and attention to detail * Strong organizational skills * Leads by example and highly collaborative with the proven ability to work in a cross-functional internal and external teams * Must be able to prioritize work effectively to ensure progression of multiple department and corporate timelines * Pro-active in identifying opportunities along with strong problem solving and negotiation skills * A strategic thinker who can generate ideas and opportunities and turn them into successful results Benefits: * Competitive salary, bonus and stock options * Comprehensive health benefits * Flexible work schedule * A fun place to work and make an impact in patients' lives TJ Elder President Pre-Clinical Development O: 413.458.6124 C: 413.207.7676 https://www.linkedin.com/in/tjelder/ [email protected]<mailto:[email protected]> [cid:[email protected]]<http://www.stem-sourcing.com/> Please Note: The information in this e-mail message is legally privileged and confidential information intended only for the use of the addressee(s) named above. If you, the reader of this message, are not the intended recipient, you are hereby notified that you should not further disseminate, distribute, or forward this e-mail message. If you have received this e-mail in error, please notify the sender as soon as possible. In addition, please delete the erroneously received message from any device/media where the message is stored.
