Hi all,

I am trying to specify a full OMEGA matrix for simulation purpose. I get issues because some diagonals are zero and some are positive. If I write

$OMEGA BLOCK(3) FIX
0.078
0 0.02
0 0 0

I get this error:
AN ERROR WAS FOUND ON LINE 34 AT THE APPROXIMATE POSITION NOTED:
  0 0 0

  224  A VARIANCE IS ZERO, BUT THE BLOCK IS NOT FIXED TO ZERO.

I know I could do:
$OMEGA BLOCK(2) FIX
0.078
0 0.02
$OMEGA FIX
0

However, that would be complicated to generate programmatically. Anyway I can tell Nonmem to use a specified OMEGA matrix as is for a simulation?

Thank you,
Philip

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