Dear NMusers: Leiden University (NL) has a postdoc position available in pharmacometrics/pediatric pharmacology. Please find the position description below.
Best wishes, Coen *The Faculty of Science *and the Leiden Academic Centre for Drug Research are* looking for a:* *Postdoc – Quantitative Pediatric Pharmacology * The Division of Systems Pharmacology and Pharmacy (SPP) of the Leiden Academic Centre for Drug Research (LACDR) aims to develop quantitative precision medicine approaches to characterize and predict variation in treatment response and enhance translational drug development strategies. Across the five current principal investigator-led research groups of our division, the main overarching research themes are focused on (i) application of quantitative modeling/pharmacometrics in clinical pharmacology to develop optimized treatment strategies, and (ii) the development and application of systems approaches to enhance translational drug development strategies. Our ambition is to impact development of personalized treatment strategies and innovative translational drug development through integration with clinical data, including patient data. We develop new methodological advances at the interface of quantitative systems- and clinical pharmacology/pharmacometrics and other disciplines such as innovative experimental disease models, emerging biomarker technologies, state-of-the art biophysical tools, and advanced statistical/ ML/ AI-approaches. >From the education perspective, our division is involved in the Bachelor/Master program of Bio-Pharmaceutical Sciences. In addition, our division is closely involved in the Master program of Pharmacy, which is jointly organized with the Leiden University Medical Center (LUMC). For more information about our division, please visit our website. *Key responsibilities * In the group Quantitative Clinical Pharmacology of Prof. Catherijne Knibbe, in close collaboration with the Pharmaceutical Sciences department of Roche Pharma Research and Early Development (pRED) in Basel, there is a position for a postdoctoral researcher who will be working on population-based and physiologically-based modelling approaches to improve drug development and therapy in children. The objective is to obtain mechanistic insight in pharmacokinetics of drugs with complex ADME that will support extrapolations of exposure and drug-drug interactions to pediatric patients. Responsibilities include the development and/or application population pharmacokinetics and physiologically-based pharmacokinetics approaches, writing of scientific publications, and contributing to teaching & training. *Selection Criteria* ● PhD degree in the area of quantitative clinical pharmacology, pharmaceutical sciences or related discipline, ● Broad experience with modeling approaches such as population PKPD modelling and/or physiologically-based PK modelling, ● Experience with relevant software packages such as R, NONMEM or other relevant software, ● Ability to work independently as well as part of a team, ● Good communication and writing skills, ● Enthusiastic, highly motivated, and independent thinker *Our organization* Working at the Faculty of Science means being part of an exciting, dynamic scientific environment which sets high standards for its students and staff. The research carried out at the Faculty of Science is diverse, ranging from computer science, mathematics, astronomy, physics, chemistry and bio-pharmaceutical sciences to biology and environmental sciences. The faculty has grown strongly in recent years and now has more than 2,300 staff and over 5,000 students. We are located at the heart of Leiden’s Bio Science Park, one of Europe’s biggest science parks, where university and business life come together. For more information, see https://www.universiteitleiden.nl/en/science. *Terms and conditions* We offer a full-time, 1 year term position, with the possibility of renewal for an additional year based on performance. The salary range for a full time position is between € 3720 – 5090 (pay scale 10-3, depending on experience). Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses (8.3 %), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. Candidates from outside the Netherlands may be eligible for a substantial tax break. *Diversity* Leiden University is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups. LACDR is a highly diverse institute, in culture, background, and gender. We stand for excellence in a caring Institute. We wish to reflect society in all aspects, as we believe that this improves the dynamics in our organization. Therefore, we support and understand the need for a work/life/family balance and consequent varying working hours and places. We believe that doing good science is fun, and goes hand in hand with a friendly culture. *Information* Enquiries can be made to Prof. Catherijne Knibbe ( c.kni...@antoniusziekenhuis.nl). If you have any questions about the procedure, please contact the secretariat of the Division of System Pharmacology and Pharmacy, Monique Tjiong (m.tji...@lacdr.leidenuniv.nl). Information about the faculty of science can be found at http://www.science.leidenuniv.nl/index.php/english/ and about Leiden University at http://www.vacancies.leiden.edu/*.* *Applications * To apply for this vacancy, please send your application to c.kni...@antoniusziekenhuis.nl using the subject heading “Application postdoc position quantitative pediatric pharmacology”. Please ensure that you upload the following additional documents (in pdf format) quoting the vacancy number: - Motivation letter - Curriculum Vitae - preferably two reference letters Only applications received *before November 10, 2023 *will be considered.
