ICON will present at ACoP2025 annual meeting a one-day workshop on Modeling 
Delays in Pharmacokinetics and Pharmacodynamics using NONMEM on Friday the 17th 
of October 2025.
Instructors: Dr Wojciech Krzyzanski; Dr Johannes Schropp

The course will provide an overview of biological systems exhibiting delays, 
concepts of lifespan driven pharmacodynamic response, modeling of cell 
maturation, transduction delays, and nonlinear mixed effect lifespan models. 
Delay differential equations (DDEs) and distributed delay differential 
equations (DDDEs) will be introduced and implemented in NONMEM 7.6. 

The course will consist of both lectures and hands-on computer exercises. 
Temporary licenses for accessing NONMEM in cloud will be provided.

Source codes for DDE and DDDE based PK/PD models and data will be available for 
downloading to the participants.  For more information please visit 
https://sites.google.com/site/delaysinpkpd

ACoP Workshop Registration details https://acop2025.eventscribe.net



Kind Regards,

Andreea Ancuta
Customer Service Lead
Pharmacometrics Department
[email protected]
http://www.ICONplc.com
 

   

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