Friday, October 17, 2025 8 am-5 pm Pricing - Member: $600, Non-Member: $800, Student/Trainee: $300 Instructors: Robert Bauer (remotely) , Brian Sandler
Workshop Outline/Description: Advanced NONMEM 7.6 course will be presented by ICON at ACOP 2025. This in-person workshop covers the description and use of features in NONMEM 7. Workshop attendees will be instructed how to specify gradient precision and how to use the FAST algorithm (new in NM 7.4) for FOCE, how to use the Monte Carlo importance sampling, stochastic approximation expectation-maximization methods, and full Bayesian methods such as Gibbs sampling and Hamiltonian no-U turn sampling (new in NM 7.4). Parallel computing and dynamic memory allocation for efficient memory usage will be described, symbolic references to thetas, etas, and sigmas, priors to sigmas, MonteCarlo search algorithms to improve FOCE estimation, built-in individual weighted residuals, bootstrap tools for simulation, and automatic stabilization against numerical exceptions. Learn to use abbreviated code features for easier modeling of inter-occasion variability, modeling additional mixed effects levels for grouping individuals, such as inter-clinical site variability, and using the DO loop feature in abbreviated code, useful for handling multiple bolus doses in models that use the analytical absorption function for multiple transit compartments. Optimal clinical design and evaluation tool is available, as well as delay differential equation solvers. Please refer to the ACoP 2025<https://acop2025.eventscribe.net/> event site for registration details. Prepare your questions for our experts and get a better understanding of why NONMEM is valuable! If you have any questions, please e-mail us at [email protected]<mailto:[email protected]> Kind Regards, Andreea Ancuta Customer Service Lead Pharmacometrics Department +44 186 532 0167 | GMT Timezone [email protected]<mailto:[email protected]> <br /><br /> ICON plc made the following annotations. ------------------------------------------------------------------------------ This e-mail transmission may contain confidential or legally privileged information that is intended only for the individual or entity named in the e-mail address. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution, or reliance upon the contents of this e-mail is strictly prohibited. If you have received this e-mail transmission in error, please reply to the sender, so that ICON plc can arrange for proper delivery, and then please delete the message. Thank You, ICON plc South County Business Park Leopardstown Dublin 18 Ireland Registered number: 145835
