This article contains a list of registry tweaks for optimizing Windows Server 2003 SP1 based appliances. I don't know if/how this translates [or doesn't] to normal servers - but the keys listed are interesting to review and consider.
Support for Windows Server 2003 SP1 on Windows Storage Server 2003-based server appliances: <http://support.microsoft.com/kb/894372/> -- ME2 ~ Finally, powerful endpoint security that ISN'T a resource hog! ~ ~ <http://www.sunbeltsoftware.com/Business/VIPRE-Enterprise/> ~
