Disable all autoplay functions, via GPO or script if you can

Check using WSUS or MBSA to see that the patch is installed for the
vulnerability Conficker exploits on all your machines

Make sure you don't have any rogue devices showing up in DHCP scopes

These might do you for starters

2009/11/20 Kelsey, John <[email protected]>

>  Looks like we're getting hit the Conficker this morning.  Sophos is
> reporting several hundred 'conficker detected/cleaned' messages, so at least
> its catching it...BUT....how do I determine the source of the infection?
> Something I can look for with wireshark or something?  Apparently there are
> some unprotected machines on the network.
>
> Any suggestions are welcome!
>
>
> *******************************
> *John C. Kelsey
> *DuBois Regional Medical Center
> (:  814.375.3073
> 2  :   814.375.4005
> *:   [email protected]
> *******************************
>
>
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-- 
"On two occasions...I have been asked, 'Pray, Mr Babbage, if you put into
the machine wrong figures, will the right answers come out?' I am not able
rightly to apprehend the kind of confusion of ideas that could provoke such
a question."

http://raythestray.blogspot.com

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