Jeff, wouldn't boosting essentially be similar to neurotransmitter recovery in 
synapses? In short term a pre-senaptic axon would be less likely to excite a 
post-synaptic dendrite due to the lack of neurotransmitter. So it's sort of a 
boosting mechanism but is inverted. There is also boosting in some of the 
mechanisms of how the short term memory works, but I guess it does the 
opposite, as it's job is to remember rather then to achieve sparsity. 

On Dec 11, 2013, at 3:55 AM, Jeff Hawkins <[email protected]> wrote:

> Great question.
>  
> Boosting or something like it is essential.  Without boosting it is possible 
> for some columns to never win (become active) and others to win too much.  We 
> started without boosting but quickly saw that the spatial pooler would have 
> this problem of columns that never won and were essentially wasted resources. 
>  So we added boosting to solve the problem.
>  
> I am not aware of anything in the biological literature that relates directly 
> to our method of boosting, but I haven’t looked either.  However, a general 
> observation is that most excitatory neurons have a low background firing 
> rate, maybe once a second or slower.  Although this has been observed and 
> noted by many neuroscientists, I am not aware of anyone studying the 
> mechanisms that might cause it.  It is possible that low background firing 
> rates could achieve the same result as boosting.  All cells will fire 
> sometime and therefore be given a chance to learn.
>  
> Jeff.
>  
> From: nupic [mailto:[email protected]] On Behalf Of Marek Otahal
> Sent: Wednesday, December 11, 2013 12:11 AM
> To: NuPIC general mailing list.
> Subject: [nupic-discuss] Boosting: biological support?
>  
> Hello,
> 
> I understand why boosting is needed and how is it implemented 
> (algorithmically), my problem is: does it have an analogy in real brains?
> 
> I'm comparing it with the inhibition (where boosting is like a counterpart) 
> which is known (local inh) from the real brains and we just implement it. Or 
> is boosting a new, artificial concept added for an improved performance?
> 
> Thanks, Mark
> 
> -- 
> Marek Otahal :o)
> _______________________________________________
> nupic mailing list
> [email protected]
> http://lists.numenta.org/mailman/listinfo/nupic_lists.numenta.org

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