Hi all,

Just wondering if anyone got a chance to test this molecule? I want to  
make sure it's not just my installation ...

cheers,

Doug



Quoting Douglas Houston <[email protected]>:

> Hi,
>
> I have observed something curious about variations in the way   
> OpenBabel assigns Gasteiger charges.
>
> For example,
>
> babel -isdf molecule.sdf -omol2 molecule_H.mol2 -h
>
> produces a molecule with an overall charge that is essentially 0.   
> However, the command
>
> babel -isdf molecule.sdf -omol2 molecule_H.mol2 -p 7.4
>
> produces a molecule that has an overall charge of -9.0. Both output   
> files have had the same number of hydrogens added. Is this what's   
> supposed to happen?
>
> I have attached the input file for others to test. This seems to   
> happen with both 2.2.3 and 2.3.0,
>
> cheers,
>
> Doug
> _____________________________________________________
> Dr. Douglas R. Houston
> Scientific Programme Coordinator / Research Associate
> Room 3.23
> Institute of Structural and Molecular Biology
> Michael Swann Building
> King's Buildings
> University of Edinburgh
> Edinburgh, EH9 3JR, UK
> Tel. 0131 650 7358
>
> -- 
> The University of Edinburgh is a charitable body, registered in
> Scotland, with registration number SC005336.
>
>




_____________________________________________________
Dr. Douglas R. Houston
Scientific Programme Coordinator / Research Associate
Room 3.23
Institute of Structural and Molecular Biology
Michael Swann Building
King's Buildings
University of Edinburgh
Edinburgh, EH9 3JR, UK
Tel. 0131 650 7358

-- 
The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.



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