> I'm on a mac running 10.13.1 and I installed openbabel using homebrew.

I’d ask the Homebrew folks, but my guess is that you’re either not using the 
right python:

% which python

Or, Homebrew is installing the Open Babel python packages into a directory that 
you’ll need to add to your Python path.

It’s also not obvious to me from the Homebrew formula whether pybel is 
installed by default:

Note that I see:
option "with-python", "Compile Python language bindings”

I’m not 100% sure how Homebrew works, but you may need to supply that option 
when installing the formula.

Hope that helps,

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