Not a bug, but ....

(a) The SMILES format supports atom-based stereochemistry. This type
of stereochemistry is axial.

(b) In any case, Open Babel does not detect axial stereochemistry

- Noel

On 17 September 2015 at 12:45, qiancheng shen <[email protected]> wrote:
> Dear Openbabel group:
>
>               I found a molecule which should have chiral atoms, but when I
> tried to convert it from SDF to canonical SMILES with babel , the chiral
> atoms disappeared.
>
>               Is this a bug?
>
>
>               The mol file of this molecule is attached. Thank you very
> much!!
>
>
> Best,
>
> Qiancheng
>
>
>
>
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