It would be interesting to see this study replicated with larger
numbers. Interesting that the rate of CS was lower in the group
which had the oxytocic ceased at 5 cm. 
Cheers
Judy


 --- Mary Murphy <[EMAIL PROTECTED]> wrote: > Interesting..
women  often as why the "drip" can't be
> discontinued once they are in active labour.  MM
> 
> 
>       .  20040322-8 For how long should oxytocin be continued
> during induction of labour? - BJOG: An International Journal
> of Obstetrics and Gynaecology , vol 111, no 4, April 2004, pp
> 331-334 Daniel-Spiegel E; Weiner Z; Ben-Shlomo I; et al -
> (2004) 
>         OBJECTIVE: To answer the question of whether oxytocin
> induction of labour should be discontinued when active labour
> begins. DESIGN: We enrolled patients admitted for induction of
> labour with oxytocin. Exclusion criteria for induction of
> labour included non-vertex presentation, past history of more
> than one caesarean delivery, multiple pregnancies, persistent
> non-reassuring fetal heart rate before induction of labour and
> estimated fetal weight of more than 4250 g. SETTING:
> Department of Obstetrics and Gynecology, Ha'Emek Medical
> Center, Afula, Israel. POPULATION: Patients who were admitted
> for induction of labour in Ha'Emek Medical Center from 1st
> February 1998 to 29th February 2000. METHODS: Patients were
> randomly divided into two groups. In group A, infusion of
> oxytocin was incremental until 5 cm dilation and maintained at
> the same level from that point throughout the labour. In group
> B, infusion of oxytocin was incremental but was discontinued
> when cervical dilatation reached 5 cm. Comparison between the
> two groups was made using Wilcoxon rank-sum test and Fisher's
> exact test. MAIN OUTCOME MEASURE: Primary outcome variable was
> duration from induction to delivery. The secondary outcome
> variables included: duration of labour stages, maximal dosage
> and total amount of oxytocin used, the use of analgesia,
> abnormalities in fetal heart rate and episodes of uterine
> hyperstimulation. We also recorded mode of delivery, together
> with maternal and neonatal outcome. RESULTS: One hundred and
> four patients participated in this study. The active phase of
> labour was shorter in group B compared with group A, but this
> difference was not statistically significant (2.6 +/- 2 vs 3.3
> +/- 2.9, P= 0.07). In group A there were six caesarean
> deliveries and in group B only three. No significant
> differences were found when the other outcome parameters were
> compared. CONCLUSIONS: There is no advantage in continuing
> oxytocin infusion after the onset of active labour. (18
> references) (Author) 
>  

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