Vitamin C protects against PROM Source: American Journal of Clinical Nutrition 2005; 81: 859-63
Evaluating the effectiveness of a dietary dose of vitamin C in preventing premature rupture of membranes.
Taking vitamin C throughout the second half of pregnancy can significantly lower the likelihood of premature rupture of membranes (PROM), research confirms.
As vitamin C plays a role in the synthesis and degradation of collagen, it is important for maintaining the chorioamniotic membranes. Consequently, it has been proprosed that vitamin C deficiency during pregnancy may be a risk factor for PROM.
To evaluate the protective effects of vitamin C supplementation, Esther Casanueva (National Institute of Perinatology, Mexico City) and colleagues randomly assigned 109 pregnant women at 20 weeks' gestation to take 100 mg vitamin C or placebo daily. Vitamin C levels were assessed every 4 weeks, and the participants were followed-up in case of PROM.
Plasma levels of vitamin C declined throughout pregnancy in both groups. In contrast, leukocyte vitamin C levels decreased in the women given placebo, but increased in the supplemented women. Meanwhile, 14 out of the 57 pregnancies in the placebo group involved PROM, compared with just four of the 52 pregnancies in women given vitamin C.
Noting that PROM is thought to trigger 40 percent or more of all preterm labors, Casanueva et al say: "supplementation could be a valuable tool in sustaining pregnancy to term."
Posted: 19 April 2005
From: Sue Cookson <[EMAIL PROTECTED]> Reply-To: [email protected] To: [email protected] Subject: Re: [ozmidwifery] ObGynWorld.com mail a colleague Date: Thu, 21 Apr 2005 12:57:24 +1000
Hi Leanne,
Could you copy the article into the body of the email please as I don't have access to that site,
Thanks, Sue
Dear Colleague, I thought this article from ObGynWorld.com might interest you:
Vitamin C protects against PROM http://www.ObGynWorld.com/international/news/2005/Week_16/Day_2/Vitamin_C_protects_a.asp
ObGynWorld.com is the essential resource in obstetrics and gynecology, offering the latest news plus feature articles and an extensive range of clinical information. Visit the site at www.ObGynWorld.com.
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Leanne Wynne Midwife in charge of "Women's Business" Mildura Aboriginal Health Service Mob 0418 371862
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