Hi Jo,
I wasn't very clear with that bit - all states use the same product in Australia and so the preservatives etc are present irrespective of the route given. The IM route however bypasses the mucosal route which is one of the body's first line of defence against foreign agents. The IM route with vit K has been linked with some cancers - some at the site of the injection. We are actually loading the muscle site with 10000-20000 times a 'normal' level of vit K and research to date has failed to understand where and how that depot of vit K is used. The cancer link has been difficult to replicate but it is usually acknowleded that the risk of cancer after IM Vit K although small, remains a possibility. The new Konakion MM was developed to make it more easily assimilated through the oral route by changing some of its components to increase the oil factor. It still has preservatives etc and so is still of question to parents, but perhaps the oral route more closely replicates normal vit K intake.

Hope this makes sense,

Sue


On 24/03/2006, at 1:11 PM, Sue Cookson wrote:

Same sort of riks/benefits as any vaccination concept - oral vs IM route with IM bypassing normal modes of K intake which is either dietary or produced in the gut, IM including preservatives etc within the product.


Hi Sue

Here in WA the same preparation is used for oral and IM vitamin K (Konakion). So the preservatives you write about in the IM are also present in the oral.

Jo

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