Hi Paivi,

I realised that you meant this message for me personally, however I did want to let list readers know that my article on the hazards of using nitrous oxide for midwives is in the March issue of MIDIRS. I wrote this article using extensive research supplied by a midwife colleague in the UK and it was primarily aimed at the British midwives who frequently use Entonox in enclosed, unventilated labour rooms, often for many hours. There are significant health effects for midwives (and probably the women as well) and I have written these up in the article.

Nitrous oxide affects DNA synthesis and removes Vitamin B12 from the body. That is probably the reason why miscarriage rates are high amongst midwives - the embryo may be damaged by either of these deficiencies and therefore not viable. It is recommended that midwives planning a pregnancy have their B12 levels checked before starting on a pregnancy and that they work in areas away from labour wards during the pregnancy (and possibly breastfeeding). There are other effects as well - chronic fatigue is also reported in midwives (and again may be a problem postnatally for women exposed to nitrous oxide for many hours during labour).

I don't know of any research that suggests a link between nitrous oxide and Downs Syndrome.

As soon as I can get this article available, you'll all have the references and full details.

Regards,

Andrea

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