It can be out of the fridge for days so long as it is kept below a certain temp ( I think it was 25oC but dont quote that) which most hospitals which are air conditioned would be. 
At certain times I have experienced episodes in which we have had a number of 'failed' inductions which has made me question the 'toxicity' of the synt given that they are all with the same batch. We did report it to our pharmacy who contacted the manufacturers who of course said there was nothing wrong with it but replaced it and the problem went away. So draw your own conclusions.
Drawing up the synt before birth is a dangerous practice and one in which I wouldn't be part of especially as the person who drew it up may not be the one who is giving it and dishes with drawn up syringes get moved and I have even seen one which was accidently moved out of the way onto the nearest flat surface which happened to be the resus cot which could have had fatal repurcussions should someone have given it to the baby by 'mistake'. The other advantage of not drawing it up is that it cant be given as quickly which is always an advantage when medddling people are in the room. I agree with the CCT with ineffective synt being a cause of PPH but you should still be waiting for signs for separation before attempting CCT anyway.
Andrea Quanchi
On 03/09/2006, at 10:01 PM, Michelle Windsor wrote:

 
 
Just a quick question.... does anyone know how long Syntocinon can be out of refrigeration before it starts loosing its effectiveness?  Where I am working at the moment there are an amazing number of PPH's, and also the common practice of drawing up the synto and having it ready often hours before the birth. 
 
 Aside from all the other medical intervention which would contribute to PPH, if controlled cord traction is started after a dose of ineffective synto, it's probably contributing to the PPH's.
 
Cheers
Michelle


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